Parkinson’s Disease Linked to Gut Microbiome

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Summary: A new study reports a link between the deterioration of motor skills in Parkinson’s disease and alterations in the composition of populations of gut bacteria.

Source: California Institute of Technology.

Caltech scientists have discovered for the first time a functional link between bacteria in the intestines and Parkinson’s disease (PD). The researchers show that changes in the composition of gut bacterial populations–or possibly gut bacteria themselves–are actively contributing to and may even cause the deterioration of motor skills that is the hallmark of this disease.

The work–which has profound implications for the treatment of PD–was performed in the laboratory of Sarkis Mazmanian, the Luis B. and Nelly Soux Professor of Microbiology and Heritage Medical Research Institute Investigator, and appears in the December 1 issue of Cell.

PD affects 1 million people in the US and up to 10 million worldwide, making it the second most common neurodegenerative disease…

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