Stiff Vessels and Low Blood Flow in the Brain Forewarn of Dementia

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Summary: Researchers report harmful plaques associated with Alzheimer’s disease may build up in the brain as a result of high blood pressure and decreased cerebral blood flow.

Source: USC Dornsife.

USC researchers plan to explore whether this early sign could be targeted by drugs already approved for treating other health conditions.

A combination of high blood pressure and decreased blood flow inside the brain may spur the build-up of harmful plaque and signal the onset of dementia, USC researchers have found.

“If you have problems with the blood vessels in the brain, then you’re going to end up with difficulty with thinking skills, cognition, memory, and ultimately this can be related to other brain pathologies such as Alzheimer’s disease,” said Daniel Nation, lead author of the study and an assistant professor of psychology at USC Dornsife.

For the study published June 1 in the journal Brain, Nation used patient…

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